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The life cycle of the 26S proteasome: from birth, through regulation and function, and onto its death

The 26S proteasome is a large, ∼2.5 MDa, multi-catalytic ATP-dependent protease complex that serves as the degrading arm of the ubiquitin system, which is the major pathway for regulated degradation of cytosolic, nuclear and membrane proteins in all eukaryotic organisms.

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Res
Asıl Yazarlar: Livneh, Ido, Cohen-Kaplan, Victoria, Cohen-Rosenzweig, Chen, Avni, Noa, Ciechanover, Aaron
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973335/
https://ncbi.nlm.nih.gov/pubmed/27444871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.86
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