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Bmi1 Functions as an Oncogene Independent of Ink4A/Arf Repression in Hepatic Carcinogenesis
Bmi1 is a polycomb group proto-oncogene that has been implicated in multiple tumor types. However, its role in HCC development has not been well studied. In this manuscript, we report that Bmi1 is over-expressed in human HCC samples. When Bmi1 expression is knocked down in human HCC cell lines, it s...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796287/ https://ncbi.nlm.nih.gov/pubmed/19934271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0333 |
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