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Bmi1 Functions as an Oncogene Independent of Ink4A/Arf Repression in Hepatic Carcinogenesis

Bmi1 is a polycomb group proto-oncogene that has been implicated in multiple tumor types. However, its role in HCC development has not been well studied. In this manuscript, we report that Bmi1 is over-expressed in human HCC samples. When Bmi1 expression is knocked down in human HCC cell lines, it s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xu, Chuan-Rui, Lee, Susie, Ho, Coral, Bommi, Prashant, Huang, Shi-Ang, Cheung, Siu Tim, Dimri, Goberdhan P., Chen, Xin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796287/
https://ncbi.nlm.nih.gov/pubmed/19934271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0333
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