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Cryo-Immunogold Electron Microscopy for Prions: Toward Identification of a Conversion Site
Prion diseases are caused by accumulation of an abnormally folded isoform (PrP(Sc)) of the cellular prion protein (PrP(C)). The subcellular distribution of PrP(Sc) and the site of its formation in brain are still unclear. We performed quantitative cryo-immunogold electron microscopy on hippocampal s...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796247/ https://ncbi.nlm.nih.gov/pubmed/19020041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4474-08.2008 |
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