Cloning and pharmacological characterization of the dog P2X7 receptor

BACKGROUND AND PURPOSE: Human and rodent P2X7 receptors exhibit differences in their sensitivity to antagonists. In this study we have cloned and characterized the dog P2X7 receptor to determine if its antagonist sensitivity more closely resembles the human or rodent orthologues. EXPERIMENTAL APPROA...

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Bibliographische Detailangaben
Hauptverfasser: Roman, S, Cusdin, FS, Fonfria, E, Goodwin, JA, Reeves, J, Lappin, SC, Chambers, L, Walter, DS, Clay, WC, Michel, AD
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2009
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795218/
https://ncbi.nlm.nih.gov/pubmed/19814727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00425.x
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