Cloning and pharmacological characterization of the dog P2X7 receptor

BACKGROUND AND PURPOSE: Human and rodent P2X7 receptors exhibit differences in their sensitivity to antagonists. In this study we have cloned and characterized the dog P2X7 receptor to determine if its antagonist sensitivity more closely resembles the human or rodent orthologues. EXPERIMENTAL APPROA...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Roman, S, Cusdin, FS, Fonfria, E, Goodwin, JA, Reeves, J, Lappin, SC, Chambers, L, Walter, DS, Clay, WC, Michel, AD
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2009
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795218/
https://ncbi.nlm.nih.gov/pubmed/19814727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00425.x
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