Cloning and pharmacological characterization of the dog P2X7 receptor

BACKGROUND AND PURPOSE: Human and rodent P2X7 receptors exhibit differences in their sensitivity to antagonists. In this study we have cloned and characterized the dog P2X7 receptor to determine if its antagonist sensitivity more closely resembles the human or rodent orthologues. EXPERIMENTAL APPROA...

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Bibliographic Details
Main Authors:	Roman, S, Cusdin, FS, Fonfria, E, Goodwin, JA, Reeves, J, Lappin, SC, Chambers, L, Walter, DS, Clay, WC, Michel, AD
Format:	Artigo
Language:	Inglês
Published:	Blackwell Publishing Ltd 2009
Subjects:	Research Papers
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2795218/ https://ncbi.nlm.nih.gov/pubmed/19814727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00425.x
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Cloning and pharmacological characterization of the dog P2X7 receptor

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