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Agonist potency at P2X(7) receptors is modulated by structurally diverse lipids

BACKGROUND AND PURPOSE: The P2X(7) receptor exhibits a high degree of plasticity with agonist potency increasing after prolonged receptor activation. In this study we investigated the ability of lipids to modulate agonist potency at P2X(7) receptors. EXPERIMENTAL APPROACH: A variety of lipids, inclu...

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Detalhes bibliográficos
Main Authors: Michel, A D, Fonfria, E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2050815/
https://ncbi.nlm.nih.gov/pubmed/17700717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707417
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