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Agonist potency at P2X(7) receptors is modulated by structurally diverse lipids

BACKGROUND AND PURPOSE: The P2X(7) receptor exhibits a high degree of plasticity with agonist potency increasing after prolonged receptor activation. In this study we investigated the ability of lipids to modulate agonist potency at P2X(7) receptors. EXPERIMENTAL APPROACH: A variety of lipids, inclu...

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Autori principali: Michel, A D, Fonfria, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2050815/
https://ncbi.nlm.nih.gov/pubmed/17700717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707417
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