Natural Sphingadienes Inhibit Akt-Dependent Signaling and Prevent Intestinal Tumorigenesis

Sphingolipid metabolites regulate cell proliferation, migration and stress responses. Alterations in sphingolipid metabolism have been proposed to contribute to carcinogenesis, cancer progression, and drug resistance. We identified a family of natural sphingolipids called sphingadienes and investiga...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fyrst, Henrik, Oskouian, Babak, Bandhuvula, Padmavathi, Gong, Yaqiong, Byun, Hoe Sup, Bittman, Robert, Lee, Andrew R., Saba, Julie D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795098/
https://ncbi.nlm.nih.gov/pubmed/19934323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2341
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