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New Design of MHC Class II Tetramers to Accommodate Fundamental Principles of Antigen Presentation
Direct identification and isolation of antigen-specific T cells became possible with the development of “MHC tetramers”, based on fluorescent avidins displaying biotinylated peptide-MHC (pMHC) complexes. This approach, extensively used for MHC class I–restricted T cells, has met very limited success...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795019/ https://ncbi.nlm.nih.gov/pubmed/19923463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902493 |
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