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Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases
A set of 6 base-modified 2′-deoxyadenosine derivatives was incorporated to diverse DNA sequences by primer extension using Vent (exo-) polymerase and the influence of the modification on cleavage by diverse restriction endonucleases was studied. While 8-substituted (Br or methyl) adenine derivatives...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2794189/ https://ncbi.nlm.nih.gov/pubmed/19820117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp845 |
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