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The Type II restriction endonuclease MvaI has dual specificity

The MvaI restriction endonuclease cuts 5′-CC↓AGG-3′/5′-CC↑TGG-3′ sites as indicated by the arrows. N4-methylation of the inner cytosines (C(m4)CAGG/C(m4)CTGG) protects the site against MvaI cleavage. Here, we show that MvaI nicks the G-strand of the related sequence (CCGGG/CCCGG, BcnI site) if the i...

詳細記述

保存先:
書誌詳細
主要な著者: Stier, Ildikó, Kiss, Antal
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001055/
https://ncbi.nlm.nih.gov/pubmed/20693529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq676
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