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Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands

Many restriction endonucleases are dimers that act symmetrically at palindromic DNA sequences, with each active site cutting one strand. In contrast, FokI acts asymmetrically at a non-palindromic sequence, cutting ‘top’ and ‘bottom’ strands 9 and 13 nucleotides downstream of the site. FokI is a mono...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sanders, Kelly L., Catto, Lucy E., Bellamy, Stuart R. W., Halford, Stephen E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673415/
https://ncbi.nlm.nih.gov/pubmed/19223323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp046
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