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Sequence-specific cleavage of RNA by Type II restriction enzymes
The ability of 223 Type II restriction endonucleases to hydrolyze RNA–DNA heteroduplex oligonucleotide substrates was assessed. Despite the significant topological and sequence asymmetry introduced when one strand of a DNA duplex is substituted by RNA we find that six restriction enzymes (AvaII, Avr...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3001074/ https://ncbi.nlm.nih.gov/pubmed/20702422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq702 |
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