Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase

Chronic generation of reactive nitrogen species (RNS) can cause DNA damage and may also directly modify DNA repair proteins. RNS-modified DNA is repaired predominantly by the base excision repair (BER) pathway, which includes the alkyladenine DNA glycosylase (AAG). The AAG active site contains sever...

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Detalhes bibliográficos
Main Authors: Jones, Larry E., Ying, Lei, Hofseth, Anne B., Jelezcova, Elena, Sobol, Robert W., Ambs, Stefan, Harris, Curtis C., Espey, Michael Graham, Hofseth, Lorne J., Wyatt, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792317/
https://ncbi.nlm.nih.gov/pubmed/19864471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp256
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