Structures of Sortase B from Staphylococcus aureus and Bacillus anthracis Reveal Catalytic Amino Acid Triad in the Active Site

Surface proteins attached by sortases to the cell wall envelope of bacterial pathogens play important roles during infection. Sorting and attachment of these proteins is directed by C-terminal signals. Sortase B of S. aureus recognizes a motif NPQTN, cleaves the polypeptide after the Thr residue, an...

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Hauptverfasser: Zhang, Rongguang, Wu, Ruiying, Joachimiak, Grazyna, Mazmanian, Sarkis K., Missiakas, Dominique M., Gornicki, Piotr, Schneewind, Olaf, Joachimiak, Andrzej
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792001/
https://ncbi.nlm.nih.gov/pubmed/15242591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2004.06.001
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