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Structures of Sortase B from Staphylococcus aureus and Bacillus anthracis Reveal Catalytic Amino Acid Triad in the Active Site

Surface proteins attached by sortases to the cell wall envelope of bacterial pathogens play important roles during infection. Sorting and attachment of these proteins is directed by C-terminal signals. Sortase B of S. aureus recognizes a motif NPQTN, cleaves the polypeptide after the Thr residue, an...

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Detalhes bibliográficos
Main Authors: Zhang, Rongguang, Wu, Ruiying, Joachimiak, Grazyna, Mazmanian, Sarkis K., Missiakas, Dominique M., Gornicki, Piotr, Schneewind, Olaf, Joachimiak, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792001/
https://ncbi.nlm.nih.gov/pubmed/15242591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2004.06.001
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