Structures of Sortase B from Staphylococcus aureus and Bacillus anthracis Reveal Catalytic Amino Acid Triad in the Active Site

Surface proteins attached by sortases to the cell wall envelope of bacterial pathogens play important roles during infection. Sorting and attachment of these proteins is directed by C-terminal signals. Sortase B of S. aureus recognizes a motif NPQTN, cleaves the polypeptide after the Thr residue, an...

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Bibliografiske detaljer
Main Authors: Zhang, Rongguang, Wu, Ruiying, Joachimiak, Grazyna, Mazmanian, Sarkis K., Missiakas, Dominique M., Gornicki, Piotr, Schneewind, Olaf, Joachimiak, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792001/
https://ncbi.nlm.nih.gov/pubmed/15242591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2004.06.001
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