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Using Lifetime Risk Estimates in Personal Genomic Profiles: Estimation of Uncertainty
Personal genome tests are now offered direct-to-consumer (DTC) via genetic variants identified by genome-wide association studies (GWAS) for common diseases. Tests report risk estimates (age-specific and lifetime) for various diseases based on genotypes at multiple loci. However, uncertainty surroun...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790579/ https://ncbi.nlm.nih.gov/pubmed/19931039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.10.017 |
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