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Estimating the contribution of genetic variants to difference in incidence of disease between population groups

Genome-wide association studies have identified multiple genetic susceptibility variants to several complex human diseases. However, risk-genotype frequency at loci showing robust associations might differ substantially among different populations. In this paper, we present methods to assess the con...

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Detalhes bibliográficos
Main Authors: Moonesinghe, Ramal, Ioannidis, John PA, Flanders, W Dana, Yang, Quanhe, Truman, Benedict I, Khoury, Muin J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400729/
https://ncbi.nlm.nih.gov/pubmed/22333905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.15
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