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Sample size requirements to detect the effect of a group of genetic variants in case-control studies
BACKGROUND: Because common diseases are caused by complex interactions among many genetic variants along with environmental risk factors, very large sample sizes are usually needed to detect such effects in case-control studies. Nevertheless, many genetic variants act in well defined biologic system...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651869/ https://ncbi.nlm.nih.gov/pubmed/19055767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-7622-5-24 |
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