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Evaluation of the discriminative accuracy of genomic profiling in the prediction of common complex diseases

Genetic testing for susceptibility to common diseases based on a combination of genetic markers may be needed because the effect size associated with each genetic marker is small. Whether or not a genome profile based on a combination of markers could yield a useful test can be evaluated by assessin...

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Detalhes bibliográficos
Main Authors: Moonesinghe, Ramal, Liu, Tiebin, Khoury, Muin J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987256/
https://ncbi.nlm.nih.gov/pubmed/19935832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.209
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