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Impaired mitochondrial trafficking in Huntington's disease
Impaired mitochondrial function has been well documented in Huntington's disease. Mutant huntingtin is found to affect mitochondria via various mechanisms including the dysregulation of gene transcription and impairment of mitochondrial function or trafficking. The lengthy and highly branched n...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2790549/ https://ncbi.nlm.nih.gov/pubmed/19591925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2009.06.008 |
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