ロード中...

Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice

Huntington's disease (HD) is caused by the expansion of a polyglutamine tract in the N-terminal region of huntingtin (htt) and is characterized by selective neurodegeneration. In addition to forming nuclear aggregates, mutant htt accumulates in neuronal processes as well as synapses and affects...

詳細記述

保存先:
書誌詳細
主要な著者: Wang, Jianjun, Wang, Chuan-En, Orr, Adam, Tydlacka, Suzanne, Li, Shi-Hua, Li, Xiao-Jiang
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290845/
https://ncbi.nlm.nih.gov/pubmed/18362179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709080
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!