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Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice
Huntington's disease (HD) is caused by the expansion of a polyglutamine tract in the N-terminal region of huntingtin (htt) and is characterized by selective neurodegeneration. In addition to forming nuclear aggregates, mutant htt accumulates in neuronal processes as well as synapses and affects...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2008
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290845/ https://ncbi.nlm.nih.gov/pubmed/18362179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709080 |
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