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Ligand and Structure-based Methodologies for the Prediction of the Activity of G Protein-Coupled Receptor Ligands

Accurate in silico models for the quantitative prediction of the activity of G protein-coupled receptor (GPCR) ligands would greatly facilitate the process of drug discovery and development. Several methodologies have been developed based on the properties of the ligands, the direct study of the rec...

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Bibliografiske detaljer
Main Authors: Costanzi, Stefano, Tikhonova, Irina G., Harden, T. Kendall, Jacobson, Kenneth A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789990/
https://ncbi.nlm.nih.gov/pubmed/18483766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-008-9218-3
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