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Ligand and Structure-based Methodologies for the Prediction of the Activity of G Protein-Coupled Receptor Ligands

Accurate in silico models for the quantitative prediction of the activity of G protein-coupled receptor (GPCR) ligands would greatly facilitate the process of drug discovery and development. Several methodologies have been developed based on the properties of the ligands, the direct study of the rec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Costanzi, Stefano, Tikhonova, Irina G., Harden, T. Kendall, Jacobson, Kenneth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789990/
https://ncbi.nlm.nih.gov/pubmed/18483766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-008-9218-3
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