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Ligand and Structure-based Methodologies for the Prediction of the Activity of G Protein-Coupled Receptor Ligands

Accurate in silico models for the quantitative prediction of the activity of G protein-coupled receptor (GPCR) ligands would greatly facilitate the process of drug discovery and development. Several methodologies have been developed based on the properties of the ligands, the direct study of the rec...

詳細記述

保存先:
書誌詳細
主要な著者: Costanzi, Stefano, Tikhonova, Irina G., Harden, T. Kendall, Jacobson, Kenneth A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789990/
https://ncbi.nlm.nih.gov/pubmed/18483766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10822-008-9218-3
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