The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity

NCB5OR is a novel flavoheme reductase with a cytochrome b5-like domain at the N-terminus and a cytochrome b5 reductase-like domain at the C terminus. Ncb5or knock-out mice develop insulin deficient diabetes and loss of white adipose tissue. Ncb5or(−/−) mice have impairment of Δ9 fatty acid desaturat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhang, Yongzhao, Larade, Kevin, Jiang, Zhi-gang, Ito, Susumu, Wang, WenFang, Zhu, Hao, Bunn, H. Franklin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789786/
https://ncbi.nlm.nih.gov/pubmed/19609006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900146-JLR200
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge