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The flavoheme reductase Ncb5or protects cells against endoplasmic reticulum stress-induced lipotoxicity

NCB5OR is a novel flavoheme reductase with a cytochrome b5-like domain at the N-terminus and a cytochrome b5 reductase-like domain at the C terminus. Ncb5or knock-out mice develop insulin deficient diabetes and loss of white adipose tissue. Ncb5or(−/−) mice have impairment of Δ9 fatty acid desaturat...

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Detalhes bibliográficos
Main Authors: Zhang, Yongzhao, Larade, Kevin, Jiang, Zhi-gang, Ito, Susumu, Wang, WenFang, Zhu, Hao, Bunn, H. Franklin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789786/
https://ncbi.nlm.nih.gov/pubmed/19609006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900146-JLR200
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