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Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease

The Postn gene encodes protein periostin. During embryonic development, it is highly expressed in the outflow tract (OFT) endocardial cushions of the developing heart, which give rise to several structures of the mature heart including the aortic valve. Periostin was previously implicated in osteobl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tkatchenko, Tatiana V., Moreno-Rodriguez, Ricardo A., Conway, Simon J., Molkentin, Jeffery D., Markwald, Roger R., Tkatchenko, Andrei V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789674/
https://ncbi.nlm.nih.gov/pubmed/19723774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00078.2009
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