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Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease
The Postn gene encodes protein periostin. During embryonic development, it is highly expressed in the outflow tract (OFT) endocardial cushions of the developing heart, which give rise to several structures of the mature heart including the aortic valve. Periostin was previously implicated in osteobl...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789674/ https://ncbi.nlm.nih.gov/pubmed/19723774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00078.2009 |
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