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Periostin Expression is Altered in Aortic Valves in Smad6 Mutant Mice

Smad6 is known to predominantly inhibit BMP signaling by negatively regulating the BMP signaling process. Therefore, Smad6 mutation potentially provides an important genetic model for investigating the role of BMP signaling in vivo. Periostin is a 90-kDA secreted extracellular matrix (ECM) protein a...

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Vydáno v:J Neonatal Biol
Hlavní autoři: Sugi, Yukiko, Kern, Michael J, Markwald, Roger R, Burnside, Jessica L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224111/
https://ncbi.nlm.nih.gov/pubmed/25383261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2167-0897.1000101
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