Inhibitory Role of Notch1 in Calcific Aortic Valve Disease

Aortic valve calcification is the most common form of valvular heart disease, but the mechanisms of calcific aortic valve disease (CAVD) are unknown. NOTCH1 mutations are associated with aortic valve malformations and adult-onset calcification in families with inherited disease. The Notch signaling...

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Detalhes bibliográficos
Main Authors: Acharya, Asha, Hans, Chetan P., Koenig, Sara N., Nichols, Haley A., Galindo, Cristi L., Garner, Harold R., Merrill, Walter H., Hinton, Robert B., Garg, Vidu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218038/
https://ncbi.nlm.nih.gov/pubmed/22110751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027743
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