Inhibitory Role of Notch1 in Calcific Aortic Valve Disease

Aortic valve calcification is the most common form of valvular heart disease, but the mechanisms of calcific aortic valve disease (CAVD) are unknown. NOTCH1 mutations are associated with aortic valve malformations and adult-onset calcification in families with inherited disease. The Notch signaling...

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Autors principals: Acharya, Asha, Hans, Chetan P., Koenig, Sara N., Nichols, Haley A., Galindo, Cristi L., Garner, Harold R., Merrill, Walter H., Hinton, Robert B., Garg, Vidu
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218038/
https://ncbi.nlm.nih.gov/pubmed/22110751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027743
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