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C-Terminal Membrane Spanning Region of Human Heme Oxygenase-1 Mediates a Time Dependent Complex Formation with Cytochrome P450 Reductase

Heme oxygenase-1 (HO-1) catalyzes the oxidative degradation of heme to biliverdin, carbon monoxide, and free iron in a reaction requiring the interaction of HO-1 with NADPH-cytochrome P450 reductase (CPR). HO-1 is bound to the endoplasmic reticulum by 23 C-terminal amino acids; however, a soluble HO...

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Bibliografske podrobnosti
Main Authors: Huber, Warren J., Scruggs, Brittni A., Backes, Wayne L.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789667/
https://ncbi.nlm.nih.gov/pubmed/19123922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801912z
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