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Heme oxygenase-1 affects cytochrome P450 function through the formation of heteromeric complexes: Interactions between CYP1A2 and heme oxygenase-1

Heme oxygenase 1 (HO-1) and the cytochromes P450 (P450s) are endoplasmic reticulum–bound enzymes that rely on the same protein, NADPH-cytochrome P450 reductase (POR), to provide the electrons necessary for substrate metabolism. Although the HO-1 and P450 systems are interconnected owing to their com...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Connick, J. Patrick, Reed, James R., Cawley, George F., Backes, Wayne L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948974/
https://ncbi.nlm.nih.gov/pubmed/33148696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015911
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