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Interactions between Cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) Lead to Alterations in Toluene Disposition and P450 Uncoupling

The goal of this study was to characterize the effects of CYP1A2•CYP2B4 complex formation on the rates and efficiency of toluene metabolism by comparing the results from simple reconstituted systems containing P450 reductase (CPR) and a single P450 to those using a mixed system containing CPR and bo...

詳細記述

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書誌詳細
主要な著者: Reed, James R., Cawley, George F., Backes, Wayne L.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750074/
https://ncbi.nlm.nih.gov/pubmed/23675771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400422a
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