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Probing the Role of Backbone Hydrogen Bonding in a Critical β-sheet of the Extracellular Domain of a Cys-loop Receptor
Long-range communication is essential for the function of members of the Cys-loop family of neurotransmitter-gated ion channels. The involvement of the peptide backbone in binding-induced conformational changes that lead to channel gating in these membrane proteins is an interesting, but unresolved...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2789490/ https://ncbi.nlm.nih.gov/pubmed/19405066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900092 |
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