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Inhibition of Wnt/Axin/β-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity

Ventral midline cells in the neural tube form floorplate throughout most of the central nervous system (CNS) but in the anterior forebrain, they differentiate with hypothalamic identity. The signalling pathways responsible for subdivision of midline neural tissue into hypothalamic and floorplate dom...

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Autors principals: Kapsimali, Marika, Caneparo, Luca, Houart, Corinne, Wilson, Stephen W.
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789262/
https://ncbi.nlm.nih.gov/pubmed/15539488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.01453
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