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Inhibition of Wnt/Axin/β-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity

Ventral midline cells in the neural tube form floorplate throughout most of the central nervous system (CNS) but in the anterior forebrain, they differentiate with hypothalamic identity. The signalling pathways responsible for subdivision of midline neural tissue into hypothalamic and floorplate dom...

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Detalhes bibliográficos
Main Authors: Kapsimali, Marika, Caneparo, Luca, Houart, Corinne, Wilson, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789262/
https://ncbi.nlm.nih.gov/pubmed/15539488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.01453
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