Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors

In eukaryotic replication licensing, Cdt1 plays a key role by recruiting the MCM2-7 complex onto the origin of chromosome. The C-terminal domain of mouse Cdt1 (mCdt1C), the most conserved region in Cdt1, is essential for licensing and directly interacts with the MCM2-7 complex. We have determined th...

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Detalhes bibliográficos
Main Authors: Khayrutdinov, Bulat I, Bae, Won Jin, Yun, Young Mi, Lee, Jie Hye, Tsuyama, Takashi, Kim, Jung Joo, Hwang, Eunha, Ryu, Kyoung-Seok, Cheong, Hae-Kap, Cheong, Chaejoon, Ko, Jung-Soon, Enomoto, Takemi, Karplus, P Andrew, Güntert, Peter, Tada, Shusuke, Jeon, Young Ho, Cho, Yunje
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788280/
https://ncbi.nlm.nih.gov/pubmed/19722278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.236
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