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Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
In eukaryotic replication licensing, Cdt1 plays a key role by recruiting the MCM2-7 complex onto the origin of chromosome. The C-terminal domain of mouse Cdt1 (mCdt1C), the most conserved region in Cdt1, is essential for licensing and directly interacts with the MCM2-7 complex. We have determined th...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788280/ https://ncbi.nlm.nih.gov/pubmed/19722278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.236 |
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