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Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway
In eukaryotic cells, apoptosis and cell cycle arrest by the Ras → RASSF → MST pathway are controlled by the interaction of SARAH (for Salvador/Rassf/Hippo) domains in the C-terminal part of tumor suppressor proteins. The Mst1 SARAH domain interacts with its homologous domain of Rassf1 and Rassf5 (al...
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Autori principali: | , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
National Academy of Sciences
2007
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1890478/ https://ncbi.nlm.nih.gov/pubmed/17517604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610716104 |
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