Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway

In eukaryotic cells, apoptosis and cell cycle arrest by the Ras → RASSF → MST pathway are controlled by the interaction of SARAH (for Salvador/Rassf/Hippo) domains in the C-terminal part of tumor suppressor proteins. The Mst1 SARAH domain interacts with its homologous domain of Rassf1 and Rassf5 (al...

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Autors principals: Hwang, Eunha, Ryu, Kyoung-Seok, Pääkkönen, Kimmo, Güntert, Peter, Cheong, Hae-Kap, Lim, Dae-Sik, Lee, Jie-Oh, Jeon, Young Ho, Cheong, Chaejoon
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890478/
https://ncbi.nlm.nih.gov/pubmed/17517604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610716104
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