SARAH Domain-Mediated MST2-RASSF Dimeric Interactions

RASSF enzymes act as key apoptosis activators and tumor suppressors, being downregulated in many human cancers, although their exact regulatory roles remain unknown. A key downstream event in the RASSF pathway is the regulation of MST kinases, which are main effectors of RASSF-induced apoptosis. The...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Sánchez-Sanz, Goar, Tywoniuk, Bartłomiej, Matallanas, David, Romano, David, Nguyen, Lan K., Kholodenko, Boris N., Rosta, Edina, Kolch, Walter, Buchete, Nicolae-Viorel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055338/
https://ncbi.nlm.nih.gov/pubmed/27716844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005051
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