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Endothelin-1 induces p66Shc activation through EGF receptor transactivation: Role of β(1)Pix/Gα(i3) interaction
Endothelin-1 (ET-1) is a vasoconstrictor peptide known to be a potent mitogen for glomerular mesangial cells. We have shown that ET-1 stimulates the adaptor protein p66Shc through Rac/Cdc42 guanine nucleotide exchange factor β(1)Pix. In this study, we demonstrate that ET-1-induced serine phosphoryla...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2788086/ https://ncbi.nlm.nih.gov/pubmed/19804820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.09.039 |
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