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The Cdc42/Rac Nucleotide Exchange Factor Protein β(1)Pix (Pak-interacting Exchange Factor) Modulates β-Catenin Transcriptional Activity in Colon Cancer Cells: EVIDENCE FOR DIRECT INTERACTION OF β(1)PIX WITH β-CATENIN
Wnt/β-catenin signaling is highly regulated and critical for intestinal epithelial development and repair; aberrant β-catenin signaling is strongly associated with colon cancer. The small GTPase Rac1 regulates β-catenin nuclear translocation and signaling. Here we tested the hypothesis that β(1)Pix,...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3837141/ https://ncbi.nlm.nih.gov/pubmed/24129564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.480103 |
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