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Targeting and activation of Rac1 are mediated by the exchange factor β-Pix

Rho guanosine triphosphatases (GTPases) are critical regulators of cytoskeletal dynamics and control complex functions such as cell adhesion, spreading, migration, and cell division. It is generally accepted that localized GTPase activation is required for the proper initiation of downstream signali...

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Detalhes bibliográficos
Main Authors: ten Klooster, Jean Paul, Jaffer, Zahara M., Chernoff, Jonathan, Hordijk, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063707/
https://ncbi.nlm.nih.gov/pubmed/16492808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200509096
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