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Distinct roles of Rac GTPases and the UNC-73/Trio and PIX-1 Rac GTP exchange factors in neuroblast protrusion and migration in C. elegans

The Rac and Cdc42 GTPases as well as the multiple GTP exchange factors that regulate their activity have been implicated in the pathways that drive actin cytoskeleton reorganization, but the individual contributions of these molecules to cell migration remain unknown. Studies shown here examine the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dyer, Jamie O, Demarco, Rafael S, Lundquist, Erik A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109480/
https://ncbi.nlm.nih.gov/pubmed/21686119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.1.1.12991
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