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Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases

The guidance cue UNC-6/Netrin regulates both attractive and repulsive axon guidance. Our previous work showed that in C. elegans, the attractive UNC-6/Netrin receptor UNC-40/DCC stimulates growth cone protrusion, and that the repulsive receptor, an UNC-5:UNC-40 heterodimer, inhibits growth cone prot...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Gujar, Mahekta R., Stricker, Aubrie M., Lundquist, Erik A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597259/
https://ncbi.nlm.nih.gov/pubmed/28859089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006998
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