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RHO-1 and the Rho GEF RHGF-1 interact with UNC-6/Netrin signaling to regulate growth cone protrusion and microtubule organization in Caenorhabditis elegans

UNC-6/Netrin is a conserved axon guidance cue that directs growth cone migrations in the dorsal-ventral axis of C. elegans and in the vertebrate spinal cord. UNC-6/Netrin is expressed in ventral cells, and growth cones migrate ventrally toward or dorsally away from UNC-6/Netrin. Recent studies of gr...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Gujar, Mahekta R., Stricker, Aubrie M., Lundquist, Erik A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611649/
https://ncbi.nlm.nih.gov/pubmed/31233487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007960
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